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Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers.
Wolpaw, Adam J; Bayliss, Richard; Büchel, Gabriele; Dang, Chi V; Eilers, Martin; Gustafson, W Clay; Hansen, Gwenn H; Jura, Natalia; Knapp, Stefan; Lemmon, Mark A; Levens, David; Maris, John M; Marmorstein, Ronen; Metallo, Steven J; Park, Julie R; Penn, Linda Z; Rape, Michael; Roussel, Martine F; Shokat, Kevan M; Tansey, William P; Verba, Kliment A; Vos, Seychelle M; Weiss, William A; Wolf, Elmar; Mossé, Yaël P.
Afiliação
  • Wolpaw AJ; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Bayliss R; Wistar Institute, Philadelphia, Pennsylvania.
  • Büchel G; Astbury Center for Structural Molecular Biology, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
  • Dang CV; Department of Biochemistry and Molecular Biology, Theodor Boveri Institute, Biocenter, University of Wuürzburg, Wuürzburg, Germany.
  • Eilers M; Mildred Scheel Early Career Center, University Hospital Wuürzburg, Wuürzburg, Germany.
  • Gustafson WC; Wistar Institute, Philadelphia, Pennsylvania.
  • Hansen GH; Ludwig Institute for Cancer Research, New York, New York.
  • Jura N; Department of Biochemistry and Molecular Biology, Theodor Boveri Institute, Biocenter, University of Wuürzburg, Wuürzburg, Germany.
  • Knapp S; University of California San Francisco, UCSF Benioff Children's Hospital, San Francisco, California.
  • Lemmon MA; Nurix Therapeutics, San Francisco, California.
  • Levens D; Cardiovascular Research Institute, University of California San Francisco, San Francisco, California.
  • Maris JM; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California.
  • Marmorstein R; Institut für Pharmazeutische Chemie und Structural Genomics Consortium, Goethe-University Frankfurt, Frankfurt, Germany.
  • Metallo SJ; Department of Pharmacology and Cancer Biology Institute, Yale School of Medicine, New Haven, Connecticut.
  • Park JR; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Penn LZ; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. mosse@chop.edu maris@chop.edu.
  • Rape M; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Roussel MF; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Shokat KM; Department of Chemistry, Georgetown University, Washington, DC.
  • Tansey WP; Department of Pediatrics, University of Washington School of Medicine and Center for Clinical and Translational Research, Seattle Children's Hospital, Seattle, Washington.
  • Verba KA; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Vos SM; Howard Hughes Medical Institute, University of California at Berkeley, Berkeley, California.
  • Weiss WA; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Wolf E; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California.
  • Mossé YP; Vanderbilt University School of Medicine, Nashville, Tennessee.
Cancer Res ; 81(7): 1627-1632, 2021 04 01.
Article em En | MEDLINE | ID: mdl-33509943
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Terapias em Estudo / Proteína Proto-Oncogênica N-Myc / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Terapias em Estudo / Proteína Proto-Oncogênica N-Myc / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article