Bringing Structural Implications and Deep Learning-Based Drug Identification for <i>KRAS</i> Mutants.

Mehmood, Aamir; Kaushik, Aman Chandra; Wang, Qiankun; Li, Cheng-Dong; Wei, Dong-Qing

Bringing Structural Implications and Deep Learning-Based Drug Identification for KRAS Mutants.

Mehmood, Aamir; Kaushik, Aman Chandra; Wang, Qiankun; Li, Cheng-Dong; Wei, Dong-Qing.

Afiliação

Mehmood A; Department of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai 200240, China.
Kaushik AC; Peng Cheng Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nanshan District, Shenzhen, Guangdong, 518055, P. R. China.
Wang Q; Wuxi School of Medicine, Jiangnan University, Li Lake Avenue, Wuxi, Jiangsu 214122, China.
Li CD; Department of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai 200240, China.
Wei DQ; Department of Bioinformatics and Biostatistics, State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai 200240, China.

J Chem Inf Model ; 61(2): 571-586, 2021 02 22.

Article em En | MEDLINE | ID: mdl-33513018

Assuntos

Neoplasias Colorretais; Aprendizado Profundo; Preparações Farmacêuticas; Códon; Neoplasias Colorretais/genética; Humanos; Simulação de Dinâmica Molecular; Mutação; Proteínas Proto-Oncogênicas p21(ras)/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Neoplasias Colorretais / Aprendizado Profundo Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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