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New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens.
Durcik, Martina; Nyerges, Ákos; Skok, Ziga; Skledar, Darja Gramec; Trontelj, Jurij; Zidar, Nace; Ilas, Janez; Zega, Anamarija; Cruz, Cristina D; Tammela, Päivi; Welin, Martin; Kimbung, Yengo R; Focht, Dorota; Benek, Ondrej; Révész, Tamás; Draskovits, Gábor; Szili, Petra Éva; Daruka, Lejla; Pál, Csaba; Kikelj, Danijel; Masic, Lucija Peterlin; Tomasic, Tihomir.
Afiliação
  • Durcik M; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Nyerges Á; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Szeged, H-6726, Hungary.
  • Skok Z; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Skledar DG; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Trontelj J; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Zidar N; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Ilas J; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Zega A; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Cruz CD; Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, P.O. Box 56 (Viikinkaari 5 E), 00014, Helsinki, Finland.
  • Tammela P; Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, P.O. Box 56 (Viikinkaari 5 E), 00014, Helsinki, Finland.
  • Welin M; SARomics Biostructures, Medicon Village, Lund, Sweden.
  • Kimbung YR; SARomics Biostructures, Medicon Village, Lund, Sweden.
  • Focht D; SARomics Biostructures, Medicon Village, Lund, Sweden.
  • Benek O; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
  • Révész T; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Szeged, H-6726, Hungary.
  • Draskovits G; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Szeged, H-6726, Hungary.
  • Szili PÉ; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Szeged, H-6726, Hungary.
  • Daruka L; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Szeged, H-6726, Hungary.
  • Pál C; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Szeged, H-6726, Hungary.
  • Kikelj D; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
  • Masic LP; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia. Electronic address: Lucija.PeterlinMasic@ffa.uni-lj.si.
  • Tomasic T; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000, Ljubljana, Slovenia. Electronic address: Tihomir.Tomasic@ffa.uni-lj.si.
Eur J Med Chem ; 213: 113200, 2021 Mar 05.
Article em En | MEDLINE | ID: mdl-33524686
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Trifosfato de Adenosina / DNA Girase / DNA Topoisomerase IV / Escherichia coli / Antibacterianos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Trifosfato de Adenosina / DNA Girase / DNA Topoisomerase IV / Escherichia coli / Antibacterianos Idioma: En Ano de publicação: 2021 Tipo de documento: Article