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Synthesis of Carboxamide-Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia.
Teresa Borrello, Maria; Benelkebir, Hanae; Lee, Adam; Hin Tam, Chak; Shafat, Manar; Rushworth, Stuart A; Bowles, Kristian M; Douglas, Leon; Duriez, Patrick J; Bailey, Sarah; Crabb, Simon J; Packham, Graham; Ganesan, A.
Afiliação
  • Teresa Borrello M; School of Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Benelkebir H; School of Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Lee A; School of Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Hin Tam C; School of Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Shafat M; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Rushworth SA; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Bowles KM; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK.
  • Douglas L; Protein Core Facility and Cancer Sciences, Cancer Research UK Centre and Experimental Cancer Medicines Centre University of Southampton Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Duriez PJ; Protein Core Facility and Cancer Sciences, Cancer Research UK Centre and Experimental Cancer Medicines Centre University of Southampton Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Bailey S; Protein Core Facility and Cancer Sciences, Cancer Research UK Centre and Experimental Cancer Medicines Centre University of Southampton Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Crabb SJ; Protein Core Facility and Cancer Sciences, Cancer Research UK Centre and Experimental Cancer Medicines Centre University of Southampton Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Packham G; Protein Core Facility and Cancer Sciences, Cancer Research UK Centre and Experimental Cancer Medicines Centre University of Southampton Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Ganesan A; School of Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
ChemMedChem ; 16(8): 1316-1324, 2021 04 20.
Article em En | MEDLINE | ID: mdl-33533576
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tranilcipromina / Inibidores Enzimáticos / Histona Desmetilases / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tranilcipromina / Inibidores Enzimáticos / Histona Desmetilases / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article