Nuclear upregulation of class I phosphoinositide 3-kinase p110ß correlates with high 47S rRNA levels in cancer cells.

Mazloumi Gavgani, Fatemeh; Karlsson, Thomas; Tangen, Ingvild L; Morovicz, Andrea Papdiné; Arnesen, Victoria Smith; Turcu, Diana C; Ninzima, Sandra; Spang, Katharina; Krakstad, Camilla; Guillermet-Guibert, Julie; Lewis, Aurélia E

Mazloumi Gavgani, Fatemeh; Karlsson, Thomas; Tangen, Ingvild L; Morovicz, Andrea Papdiné; Arnesen, Victoria Smith; Turcu, Diana C; Ninzima, Sandra; Spang, Katharina; Krakstad, Camilla; Guillermet-Guibert, Julie; Lewis, Aurélia E.

Afiliação

Mazloumi Gavgani F; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Karlsson T; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Tangen IL; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen 5021, Norway.
Morovicz AP; Department of Gynaecology and Obstetrics, Haukeland University Hospital, Bergen 5021, Norway.
Arnesen VS; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Turcu DC; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Ninzima S; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Spang K; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Krakstad C; Department of Biological Sciences, University of Bergen, Bergen 5008, Norway.
Guillermet-Guibert J; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen 5021, Norway.
Lewis AE; Department of Gynaecology and Obstetrics, Haukeland University Hospital, Bergen 5021, Norway.

J Cell Sci ; 134(3)2021 02 10.

Article em En | MEDLINE | ID: mdl-33536247

Assuntos

Neoplasias do Endométrio; Fosfatidilinositol 3-Quinase; Proliferação de Células/genética; Neoplasias do Endométrio/genética; Feminino; Humanos; Fosfatidilinositol 3-Quinases/genética; Fosfatidilinositol 3-Quinases/metabolismo; Regulação para Cima/genética

Palavras-chave

Endometrial cancer; Nucleolus; PIK3CB; Phosphoinositide 3-kinase; p110ß; rDNA transcription

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Endométrio / Fosfatidilinositol 3-Quinase Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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