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BIG BANG study (EPOC1703): multicentre, proof-of-concept, phase II study evaluating the efficacy and safety of combination therapy with binimetinib, encorafenib and cetuximab in patients with BRAF non-V600E mutated metastatic colorectal cancer.
Kotani, Daisuke; Bando, Hideaki; Taniguchi, Hiroya; Masuishi, Toshiki; Komatsu, Yoshito; Yamaguchi, Kensei; Nakajima, Takako; Satoh, Taroh; Nishina, Tomohiro; Esaki, Taito; Nomura, Shogo; Takahashi, Koji; Iida, Shinobu; Matsuda, Seiko; Motonaga, Shinya; Fuse, Nozomu; Sato, Akihiro; Fujii, Satoshi; Ohtsu, Atsushi; Ebi, Hiromichi; Yoshino, Takayuki.
Afiliação
  • Kotani D; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Bando H; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan. Electronic address: hbando@aichi-cc.jp.
  • Taniguchi H; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Masuishi T; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Komatsu Y; Department of Cancer Chemotherapy, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
  • Yamaguchi K; Department of Gastroenterological Medicine, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Nakajima T; Department of Clinical Oncology, St. Marianna University School of Medicine, Kawasaki, Japan.
  • Satoh T; Frontier Science for Cancer and Chemotherapy, Osaka University, Suita, Osaka, Japan.
  • Nishina T; Department of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
  • Esaki T; Department of Gastrointestinal and Medical Oncology, National Kyushu Cancer Center, Fukuoka, Japan.
  • Nomura S; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Takahashi K; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Iida S; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Matsuda S; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Motonaga S; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Fuse N; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Sato A; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Fujii S; Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Ohtsu A; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan.
  • Ebi H; Division of Oncological Pathology, Aichi Cancer Center Research Institute, Nagoya, Aichi, Japan.
  • Yoshino T; Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
ESMO Open ; 5(1): e000624, 2020.
Article em En | MEDLINE | ID: mdl-33551068
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Idioma: En Ano de publicação: 2020 Tipo de documento: Article