Your browser doesn't support javascript.
loading
Organizing pneumonia: A late phase complication of COVID-19 responding dramatically to corticosteroids.
de Oliveira Filho, Cilomar Martins; Vieceli, Tarsila; de Fraga Bassotto, Caroline; da Rosa Barbato, João Pedro; Garcia, Tiago Severo; Scheffel, Rafael Selbach.
Afiliação
  • de Oliveira Filho CM; Internal Medicine Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  • Vieceli T; Internal Medicine Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  • de Fraga Bassotto C; Internal Medicine Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  • da Rosa Barbato JP; Internal Medicine Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  • Garcia TS; Radiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  • Scheffel RS; Internal Medicine Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; Universidade Federal do Rio Grande do Sul, Instituto de Ciências Básicas da Saúde, Pharmacology Department, Porto Alegre, Brazil. Electronic address: rscheffel@hcpa.edu.br.
Braz J Infect Dis ; 25(1): 101541, 2021.
Article em En | MEDLINE | ID: mdl-33567251
Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1 mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization. Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / COVID-19 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / COVID-19 Idioma: En Ano de publicação: 2021 Tipo de documento: Article