The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types.

Daniloski, Zharko; Jordan, Tristan X; Ilmain, Juliana K; Guo, Xinyi; Bhabha, Gira; tenOever, Benjamin R; Sanjana, Neville E

Daniloski, Zharko; Jordan, Tristan X; Ilmain, Juliana K; Guo, Xinyi; Bhabha, Gira; tenOever, Benjamin R; Sanjana, Neville E.

Afiliação

Daniloski Z; New York Genome Center, New York, United States.
Jordan TX; Department of Biology, New York University, New York, United States.
Ilmain JK; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States.
Guo X; Department of Cell Biology and Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, United States.
Bhabha G; New York Genome Center, New York, United States.
tenOever BR; Department of Biology, New York University, New York, United States.
Sanjana NE; Department of Cell Biology and Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, United States.

Elife ; 102021 02 11.

Article em En | MEDLINE | ID: mdl-33570490

Assuntos

COVID-19/virologia; Mutação de Sentido Incorreto; SARS-CoV-2/metabolismo; Glicoproteína da Espícula de Coronavírus/genética; Enzima de Conversão de Angiotensina 2/genética; Enzima de Conversão de Angiotensina 2/metabolismo; COVID-19/genética; COVID-19/metabolismo; Humanos; SARS-CoV-2/genética; Glicoproteína da Espícula de Coronavírus/metabolismo

Palavras-chave

COVID-19; D614G; SARS-CoV-2; Spike; coronavirus; epidemiology; global health; human; infectious disease; microbiology; virus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mutação de Sentido Incorreto / Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 / COVID-19 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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