The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner.

Skurski, Joseph; Dixit, Garima; Blobel, Carl P; Issuree, Priya D; Maretzky, Thorsten

Skurski, Joseph; Dixit, Garima; Blobel, Carl P; Issuree, Priya D; Maretzky, Thorsten.

Afiliação

Skurski J; Inflammation Program, Roy J. and Lucille A. Carver College of Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.
Dixit G; Immunology Graduate Program, Roy J. and Lucille A. Carver College of Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.
Blobel CP; Inflammation Program, Roy J. and Lucille A. Carver College of Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.
Issuree PD; Departments of Medicine and of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY, United States.
Maretzky T; Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, NY, United States.

Front Cell Infect Microbiol ; 10: 620392, 2020.

Article em En | MEDLINE | ID: mdl-33585287

Assuntos

Proteínas de Transporte; Lipopolissacarídeos; Humanos; Inflamação; Peptídeos e Proteínas de Sinalização Intracelular; Macrófagos/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

ADAM17; LPS; TNF; a disintegrin and metalloproteinase 17; iRhom2; inactive rhomboid 2; lipopolysaccharide; tumor necrosis factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Lipopolissacarídeos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Lipopolissacarídeos Idioma: En Ano de publicação: 2020 Tipo de documento: Article