Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.

Wyler, Emanuel; Mösbauer, Kirstin; Franke, Vedran; Diag, Asija; Gottula, Lina Theresa; Arsiè, Roberto; Klironomos, Filippos; Koppstein, David; Hönzke, Katja; Ayoub, Salah; Buccitelli, Christopher; Hoffmann, Karen; Richter, Anja; Legnini, Ivano; Ivanov, Andranik; Mari, Tommaso; Del Giudice, Simone; Papies, Jan; Praktiknjo, Samantha; Meyer, Thomas F; Müller, Marcel Alexander; Niemeyer, Daniela; Hocke, Andreas; Selbach, Matthias; Akalin, Altuna; Rajewsky, Nikolaus; Drosten, Christian; Landthaler, Markus

Wyler, Emanuel; Mösbauer, Kirstin; Franke, Vedran; Diag, Asija; Gottula, Lina Theresa; Arsiè, Roberto; Klironomos, Filippos; Koppstein, David; Hönzke, Katja; Ayoub, Salah; Buccitelli, Christopher; Hoffmann, Karen; Richter, Anja; Legnini, Ivano; Ivanov, Andranik; Mari, Tommaso; Del Giudice, Simone; Papies, Jan; Praktiknjo, Samantha; Meyer, Thomas F; Müller, Marcel Alexander; Niemeyer, Daniela; Hocke, Andreas; Selbach, Matthias; Akalin, Altuna; Rajewsky, Nikolaus; Drosten, Christian; Landthaler, Markus.

Afiliação

Wyler E; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Mösbauer K; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
Franke V; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Diag A; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Gottula LT; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
Arsiè R; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Klironomos F; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Koppstein D; Department of Pediatrics, Charité - University Hospital Berlin, 13353 Berlin, Germany.
Hönzke K; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Ayoub S; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine, Berlin, Germany.
Buccitelli C; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Hoffmann K; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Richter A; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine, Berlin, Germany.
Legnini I; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
Ivanov A; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Mari T; Core Unit Bioinformatics, Berlin Institute of Health, Charité - University Hospital Berlin, 10117 Berlin, Germany.
Del Giudice S; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Papies J; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Praktiknjo S; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
Meyer TF; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Müller MA; Laboratory of Infection Oncology, Institute of Clinical Molecular Biology, UKSH, Christian Albrechts University of Kiel, 24105 Kiel, Germany.
Niemeyer D; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
Hocke A; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.
Selbach M; Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine, Berlin, Germany.
Akalin A; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
Rajewsky N; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Drosten C; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Hannoversche Str 28, 10115 Berlin, Germany.
Landthaler M; Institute of Virology, Charité-Universitätsmedizin Berlin and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.