Venous Thromboembolism in Sickle Cell Disease is Associated with Neutrophilia.
Hemoglobin
; 45(1): 56-59, 2021 Jan.
Article
em En
| MEDLINE
| ID: mdl-33588667
ABSTRACT
Venous thromboembolism (VTE) in individuals with sickle cell disease is common and portends a poor prognosis. The role of leukocyte count and its subsets on risk of VTE in sickle cell disease are not known. We conducted a retrospective case-control study and analyzed for leukocyte count at the time of VTE and 3 months prior. Leukocyte and neutrophil counts were elevated at the time of VTE (p = 0.003 and p = 0.0006, respectively) and 3 months prior (p = 0.001 and p = 0.0096, respectively) when compared to controls. Baseline leukocytosis and neutrophilia may be associated with subsequent risk for thrombosis in sickle cell disease.
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Base de dados:
MEDLINE
Assunto principal:
Tromboembolia Venosa
/
Anemia Falciforme
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article