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Transient prenatal ruxolitinib treatment suppresses astrogenesis during development and improves learning and memory in adult mice.
Lee, Han-Chung; Hamzah, Hamizun; Leong, Melody Pui-Yee; Md Yusof, Hadri; Habib, Omar; Zainal Abidin, Shahidee; Seth, Eryse Amira; Lim, Siong-Meng; Vidyadaran, Sharmili; Mohd Moklas, Mohamad Aris; Abdullah, Maizaton Atmadini; Nordin, Norshariza; Hassan, Zurina; Cheah, Pike-See; Ling, King-Hwa.
Afiliação
  • Lee HC; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Hamzah H; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Leong MP; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Md Yusof H; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Habib O; Department of Biotechnology, Faculty of Science, Technology, Engineering and Mathematics, International University of Malaya-Wales, 50480, Kuala Lumpur, Malaysia.
  • Zainal Abidin S; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Seth EA; Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia.
  • Lim SM; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Vidyadaran S; Collaborative Drug Discovery Research, Faculty of Pharmacy, Universiti Teknologi MARA, Cawangan Selangor, Kampus Puncak Alam, 42300, Bandar Puncak Alam, Selangor, Malaysia.
  • Mohd Moklas MA; Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Abdullah MA; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Nordin N; Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Hassan Z; Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Cheah PS; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
  • Ling KH; Genetics and Regenerative Medicine Research Centre, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Sci Rep ; 11(1): 3847, 2021 02 15.
Article em En | MEDLINE | ID: mdl-33589712
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Astrócitos / Exposição Materna / Inibidores de Proteínas Quinases / Neurogênese / Aprendizagem / Memória / Nitrilas Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Astrócitos / Exposição Materna / Inibidores de Proteínas Quinases / Neurogênese / Aprendizagem / Memória / Nitrilas Idioma: En Ano de publicação: 2021 Tipo de documento: Article