Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead.

Ippolito, Joseph A; Niu, Haichan; Bertoletti, Nicole; Carter, Zachary J; Jin, Shengyan; Spasov, Krasimir A; Cisneros, José A; Valhondo, Margarita; Cutrona, Kara J; Anderson, Karen S; Jorgensen, William L.

Afiliação

Ippolito JA; Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, United States.
Niu H; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520-8066, United States.
Bertoletti N; Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, United States.
Carter ZJ; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520-8066, United States.
Jin S; Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, United States.
Spasov KA; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520-8066, United States.
Cisneros JA; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520-8066, United States.
Valhondo M; Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, United States.
Cutrona KJ; Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, United States.
Anderson KS; Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, United States.
Jorgensen WL; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520-8066, United States.

ACS Med Chem Lett ; 12(2): 249-255, 2021 Feb 11.

Article em En | MEDLINE | ID: mdl-33603971

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article