Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra).
Nat Prod Res
; 36(6): 1441-1447, 2022 Mar.
Article
em En
| MEDLINE
| ID: mdl-33605169
ABSTRACT
AeP-P-2, a pectic polysaccharide, was extracted from the fruit pod of okra. It composed of rhamnose (Rha), arabinose (Ara), glucose (Glc), galactose (Gal) and galacturonic acid (GalA) with the ratio of 4.752.011.004.917.24. The main structural feature of AeP-P-2 are 1,4-linked galacturonan units (homogalacturonan backbone) and (1 â 2) and (1 â 2,4) linked Rha (rhamnogalacturonan I region). And the other side chains contained â1)-linked Ara, (1 â 5)-linked Ara, (1 â 4)-linked Glc, (1 â 6)-linked Gal, (1 â 4)-linked Rha, (1 â 2,4)-linked Rha, â1)-linked Ara and â1)-linked Gal. When the concentration of AeP-P-2 was 3.2 mg/mL, the scavenging rates on DPPH·, ABTS, O2-· and ·OH reached to 61.88%, 87.10%, 52.17% and 60.32%, respectively. AeP-P-2 also could protect PC12 cells from the damage of H2O2 and reduce apoptosis caused by oxidative damage by decreasing the level of ROS. The findings indicated that okra was a functional vegetable and AeP-P-2 was worth studying and developing into antioxidant component.
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MEDLINE
Assunto principal:
Abelmoschus
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En
Ano de publicação:
2022
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Article