Fungal Polysaccharides Promote Protective Immunity.
Trends Microbiol
; 29(5): 379-381, 2021 05.
Article
em En
| MEDLINE
| ID: mdl-33610450
ABSTRACT
Fungal pathogens represent a rising threat against immunocompromised patients. By using Aspergillus fumigatus, Briard et al. showed that the cell wall galactosaminogalactan (GAG) triggers macrophage inflammasome activation, promoting protective immunity. This provides new insights into the role of GAG in host-pathogen interactions and also perspectives for developing GAG-based anti-inflammatory therapeutics.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas Fúngicas
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Interações Hospedeiro-Patógeno
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Polissacarídeos Fúngicos
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article