Secretome and Comparative Proteomics of Yersinia pestis Identify Two Novel E3 Ubiquitin Ligases That Contribute to Plague Virulence.

Cao, Shiyang; Chen, Yuling; Yan, Yanfeng; Zhu, Songbiao; Tan, Yafang; Wang, Tong; Song, Yajun; Deng, Haiteng; Yang, Ruifu; Du, Zongmin

Cao, Shiyang; Chen, Yuling; Yan, Yanfeng; Zhu, Songbiao; Tan, Yafang; Wang, Tong; Song, Yajun; Deng, Haiteng; Yang, Ruifu; Du, Zongmin.

Afiliação

Cao S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Chen Y; MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China.
Yan Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Zhu S; MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China.
Tan Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Wang T; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Song Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Deng H; MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, China. Electronic address: dht@mail.tsinghua.edu.cn.
Yang R; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China. Electronic address: ruifuyang@gmail.com.
Du Z; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China. Electronic address: zmduams@163.com.

Mol Cell Proteomics ; 20: 100066, 2021.

Article em En | MEDLINE | ID: mdl-33631294

Assuntos

Proteínas de Bactérias/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Yersinia pestis/metabolismo; Yersinia pestis/patogenicidade; Animais; Proteínas de Bactérias/genética; Feminino; Células HeLa; Humanos; Camundongos Endogâmicos BALB C; Mutação; Peste; Proteômica; Secretoma; Ubiquitina-Proteína Ligases/genética; Virulência; Yersinia pestis/genética

Palavras-chave

E3 ubiquitin ligases; Yersinia pestis; comparative proteomics; secretome; virulence

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Yersinia pestis / Ubiquitina-Proteína Ligases Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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