Topical application of sebacoyl dinalbuphine ester-loaded nanostructured lipid carriers alleviate pruritus in scratching mouse model.

Lin, Shang-Wen; Shyong, Yan-Jye; Kuo, Ping-Chung; Tsai, Jui-Chen

Lin, Shang-Wen; Shyong, Yan-Jye; Kuo, Ping-Chung; Tsai, Jui-Chen.

Afiliação

Lin SW; School of Pharmacy and Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, No.1, University Road, Tainan City 701, Taiwan.
Shyong YJ; School of Pharmacy and Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, No.1, University Road, Tainan City 701, Taiwan.
Kuo PC; School of Pharmacy and Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, No.1, University Road, Tainan City 701, Taiwan.
Tsai JC; School of Pharmacy and Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, No.1, University Road, Tainan City 701, Taiwan. Electronic address: jctsai@mail.ncku.edu.tw.

Int J Pharm ; 600: 120400, 2021 May 01.

Article em En | MEDLINE | ID: mdl-33636328

Assuntos

Nalbufina; Nanoestruturas; Animais; Portadores de Fármacos; Humanos; Lipídeos; Camundongos; Nalbufina/análogos & derivados; Tamanho da Partícula; Prurido/tratamento farmacológico

Palavras-chave

Antipruritus; Nalbuphine (NA); Nanostructured lipid carriers (NLC); Prodrug; Sebacoyl dinalbuphine ester (SDE); Topical delivery

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanoestruturas / Nalbufina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanoestruturas / Nalbufina Idioma: En Ano de publicação: 2021 Tipo de documento: Article