Impact of VSIG4 gene polymorphisms on susceptibility and functional status of rheumatoid arthritis.
Int J Immunogenet
; 48(3): 260-265, 2021 Jun.
Article
em En
| MEDLINE
| ID: mdl-33645007
ABSTRACT
The complement receptor of the immunoglobulin superfamily (CRIg, encoded by the VSIG4 gene) is a macrophage receptor involved in the clearance of immune complexes and autologous cells. Our results suggest that the VSIG4 rs1044165T allele is a risk factor for severe functional status of rheumatoid arthritis in women, possibly by affecting VSIG4 gene expression.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Receptores de Complemento
/
Predisposição Genética para Doença
/
Estudos de Associação Genética
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article