Phenotypic Models of CAR T-Cell Activation Elucidate the Pivotal Regulatory Role of CAR Downmodulation.

Greenman, Raanan; Pizem, Yoav; Haus-Cohen, Maya; Horev, Guy; Denkberg, Galit; Shen-Orr, Shai; Rubinstein, Jacob; Reiter, Yoram

Greenman, Raanan; Pizem, Yoav; Haus-Cohen, Maya; Horev, Guy; Denkberg, Galit; Shen-Orr, Shai; Rubinstein, Jacob; Reiter, Yoram.

Afiliação

Greenman R; Laboratory of Molecular Immunology, Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Pizem Y; Laboratory of Molecular Immunology, Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Haus-Cohen M; Laboratory of Molecular Immunology, Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Horev G; Laboratory of Molecular Immunology, Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Denkberg G; Adicet Bio Israel Ltd., Haifa, Israel.
Shen-Orr S; Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Rubinstein J; Faculty of Mathematics, Technion-Israel Institute of Technology, Haifa, Israel.
Reiter Y; Laboratory of Molecular Immunology, Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel. reiter@technion.ac.il.

Mol Cancer Ther ; 20(5): 946-957, 2021 05.

Article em En | MEDLINE | ID: mdl-33649103

Assuntos

Receptores de Antígenos Quiméricos/metabolismo; Linfócitos T/metabolismo; Animais; Humanos; Camundongos; Modelos Teóricos; Fenótipo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Receptores de Antígenos Quiméricos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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