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Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes.
Huang, Shar-Yin N; Michaels, Stephanie A; Mitchell, Brianna B; Majdalani, Nadim; Vanden Broeck, Arnaud; Canela, Andres; Tse-Dinh, Yuk-Ching; Lamour, Valerie; Pommier, Yves.
Afiliação
  • Huang SN; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA. shar-yin.huang@nih.gov pommier@nih.gov.
  • Michaels SA; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Mitchell BB; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Majdalani N; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Vanden Broeck A; Integrated Structural Biology Department, IGBMC, UMR7104 CNRS, U1258 Inserm, University of Strasbourg, Illkirch 67404, France.
  • Canela A; The Hakubi Center for Advanced Research, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Tse-Dinh YC; Department of Chemistry and Biochemistry, Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USA.
  • Lamour V; Integrated Structural Biology Department, IGBMC, UMR7104 CNRS, U1258 Inserm, University of Strasbourg, Illkirch 67404, France.
  • Pommier Y; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA. shar-yin.huang@nih.gov pommier@nih.gov.
Sci Adv ; 7(10)2021 03.
Article em En | MEDLINE | ID: mdl-33658195
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolonas / DNA Girase Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolonas / DNA Girase Idioma: En Ano de publicação: 2021 Tipo de documento: Article