Non-alcoholic fatty liver disease - a procoagulant condition?
Croat Med J
; 62(1): 25-33, 2021 Feb 28.
Article
em En
| MEDLINE
| ID: mdl-33660958
ABSTRACT
Non-alcoholic fatty liver disease (NAFLD) is associated with a number of extrahepatic comorbidities and considerable cardiovascular morbidity and mortality, which is possibly related to coagulation changes associated with metabolic syndrome. Coagulation disorders are common in patients with liver disease of any etiology, and here we review possible alterations in coagulation cascade specific to NAFLD. We discuss derangements in the coagulation cascade and fibrinolysis, endothelial dysfunction, and platelet abnormalities as possible culprits for altered coagulation and explore the significance of these changes for potential treatment targets.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome Metabólica
/
Hepatopatia Gordurosa não Alcoólica
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article