Myeloproliferative Neoplasms: The Long Wait for JAK2-Mutant Clone Expansion.
Cell Stem Cell
; 28(3): 359-361, 2021 03 04.
Article
em En
| MEDLINE
| ID: mdl-33667352
Myeloproliferative neoplasms (MPNs) are hematological malignancies caused by somatic mutations originating from a single hematopoietic stem cell (HSC). In this issue of Cell Stem Cell,Van Egeren et al. (2021) used whole-genome sequencing of hematopoietic colonies to reconstruct the clonal history and time of acquisition of the disease-initiating gene mutation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Hematológicas
/
Transtornos Mieloproliferativos
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article