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Myeloproliferative Neoplasms: The Long Wait for JAK2-Mutant Clone Expansion.
Luque Paz, Damien; Ashcroft, Peter; Skoda, Radek C.
Afiliação
  • Luque Paz D; Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, Basel, Switzerland.
  • Ashcroft P; Institute of Integrative Biology, ETH Zürich, Zürich, Switzerland.
  • Skoda RC; Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, Basel, Switzerland. Electronic address: radek.skoda@unibas.ch.
Cell Stem Cell ; 28(3): 359-361, 2021 03 04.
Article em En | MEDLINE | ID: mdl-33667352
Myeloproliferative neoplasms (MPNs) are hematological malignancies caused by somatic mutations originating from a single hematopoietic stem cell (HSC). In this issue of Cell Stem Cell,Van Egeren et al. (2021) used whole-genome sequencing of hematopoietic colonies to reconstruct the clonal history and time of acquisition of the disease-initiating gene mutation.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Hematológicas / Transtornos Mieloproliferativos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Hematológicas / Transtornos Mieloproliferativos Idioma: En Ano de publicação: 2021 Tipo de documento: Article