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The Co-mutational Spectrum Determines the Therapeutic Response in Murine FGFR2 Fusion-Driven Cholangiocarcinoma.
Kendre, Gajanan; Marhenke, Silke; Lorz, Georgina; Becker, Diana; Reineke-Plaaß, Tanja; Poth, Tanja; Murugesan, Karthikeyan; Kühnel, Florian; Woller, Norman; Wirtz, Ralph M; Pich, Andreas; Marquardt, Jens U; Saborowski, Michael; Vogel, Arndt; Saborowski, Anna.
Afiliação
  • Kendre G; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Marhenke S; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Lorz G; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Becker D; Department of Medicine I, Lichtenberg Research Group, Johannes Gutenberg University, Mainz, Germany.
  • Reineke-Plaaß T; Department of Pathology, Hannover Medical School, Hannover, Germany.
  • Poth T; Center for Model System and Comparative Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Murugesan K; Cancer Genomics Research, Foundation Medicine Inc., Cambridge, MD, USA.
  • Kühnel F; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Woller N; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Wirtz RM; Stratifyer Molecular Pathology, Cologne, Germany.
  • Pich A; Core Unit Mass Spectrometry and Proteomics, Hannover Medical School, Hannover, Germany.
  • Marquardt JU; First Department of Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
  • Saborowski M; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Vogel A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Saborowski A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Hepatology ; 74(3): 1357-1370, 2021 09.
Article em En | MEDLINE | ID: mdl-33709535

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Ductos Biliares Intra-Hepáticos / Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Colangiocarcinoma / Receptor Tipo 2 de Fator de Crescimento de Fibroblastos / Fusão Gênica / Neoplasias Hepáticas Experimentais Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Ductos Biliares Intra-Hepáticos / Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Colangiocarcinoma / Receptor Tipo 2 de Fator de Crescimento de Fibroblastos / Fusão Gênica / Neoplasias Hepáticas Experimentais Idioma: En Ano de publicação: 2021 Tipo de documento: Article