The concurrence of multiple sclerosis and glioblastoma.
Mult Scler Relat Disord
; 50: 102877, 2021 May.
Article
em En
| MEDLINE
| ID: mdl-33711579
ABSTRACT
INTRODUCTION:
Glioblastoma rarely coincides with multiple sclerosis. Although registries have reported a higher proportion of brain tumors-most of which are glial-these events appear to be underreported. The relative contribution of JC virus (an oncogenic virus) and disease modifying therapies that may facilitate JC virus neurotropism and tumor-specific immune evasion remain unknown. CASE REPORT We present the case of a 64-year-old woman who developed a primary glioblastoma eight years after diagnosis of multiple sclerosis while on dimethyl fumarate.CONCLUSION:
Systematic reporting may help answer whether JC virus seropositivity and certain disease modifying therapies confer higher risk for glioblastoma in patients with multiple sclerosis.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Glioblastoma
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Vírus JC
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Esclerose Múltipla Recidivante-Remitente
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Esclerose Múltipla
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article