Cell Immunity in Implant-Associated Infections Caused by Biofilm-Forming Microorganisms.
Bull Exp Biol Med
; 170(4): 458-460, 2021 Feb.
Article
em En
| MEDLINE
| ID: mdl-33713222
ABSTRACT
High biofilm-forming capacity of Staphylococcus spp. strains isolated from biomaterial of patients with infectious complications after primary knee replacement developed within 6-12 months after surgery was experimentally demonstrated. Differential leukocyte counts and some indicators of cell immunity in these patients were compared with those in patients without purulent complications and healthy volunteers. In patients with implant-associated infection, the relative numbers of T cells (both T-helpers and T-suppressors) B cells were significantly (p<0.05) reduced, while the number of NK cells was significantly increased in comparison with the corresponding parameters in other groups. The revealed changes attest to cell immunity failure in biofilm infection.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Biofilmes
/
Imunidade Celular
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article