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UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication.
Biasin, Mara; Bianco, Andrea; Pareschi, Giovanni; Cavalleri, Adalberto; Cavatorta, Claudia; Fenizia, Claudio; Galli, Paola; Lessio, Luigi; Lualdi, Manuela; Tombetti, Enrico; Ambrosi, Alessandro; Redaelli, Edoardo Maria Alberto; Saulle, Irma; Trabattoni, Daria; Zanutta, Alessio; Clerici, Mario.
Afiliação
  • Biasin M; Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
  • Bianco A; Italian National Institute for Astrophysics (INAF)-Brera Astronomical Observatory, Merate, Italy.
  • Pareschi G; Italian National Institute for Astrophysics (INAF)-Brera Astronomical Observatory, Merate, Italy.
  • Cavalleri A; Epidemiology and Prevention Unit, IRCCS Foundation, Istituto Nazionale dei Tumori, Milan, Italy.
  • Cavatorta C; Epidemiology and Prevention Unit, IRCCS Foundation, Istituto Nazionale dei Tumori, Milan, Italy.
  • Fenizia C; Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
  • Galli P; University Life and Health San Raffaele, Milan, Italy.
  • Lessio L; Italian National Institute for Astrophysics (INAF)-Brera Astronomical Observatory, Merate, Italy.
  • Lualdi M; Italian National Institute for Astrophysics (INAF)-Padova Astronomical Observatory, Padova, Italy.
  • Tombetti E; Department of Imaging Diagnostic and Radioterapy, IRCCS Foundation, Istituto Nazionale dei Tumori, Milan, Italy.
  • Ambrosi A; Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
  • Redaelli EMA; University Life and Health San Raffaele, Milan, Italy.
  • Saulle I; Italian National Institute for Astrophysics (INAF)-Brera Astronomical Observatory, Merate, Italy.
  • Trabattoni D; Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
  • Zanutta A; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
  • Clerici M; Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
Sci Rep ; 11(1): 6260, 2021 03 18.
Article em En | MEDLINE | ID: mdl-33737536
ABSTRACT
The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Replicação Viral / Inativação de Vírus / SARS-CoV-2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Replicação Viral / Inativação de Vírus / SARS-CoV-2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article