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Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial.
Braithwaite, Irene E; Cai, Fang; Tom, Jennifer A; Galanter, Joshua M; Owen, Ryan P; Zhu, Rui; Williams, Mathew; McGregor, Anna G; Eliahu, Avi; Durk, Matthew R; Dengler, Hart S; Zak, Mark; Kenny, Jane R; Wilson, Maria E; Beasley, Richard; Chen, Hubert.
Afiliação
  • Braithwaite IE; Medical Research Institute of New Zealand, Wellington, New Zealand. Electronic address: irene.braithwaite@mrinz.ac.nz.
  • Cai F; Genentech, Inc, South San Francisco, Calif.
  • Tom JA; Genentech, Inc, South San Francisco, Calif.
  • Galanter JM; Genentech, Inc, South San Francisco, Calif.
  • Owen RP; Genentech, Inc, South San Francisco, Calif.
  • Zhu R; Genentech, Inc, South San Francisco, Calif.
  • Williams M; Medical Research Institute of New Zealand, Wellington, New Zealand.
  • McGregor AG; Genentech, Inc, South San Francisco, Calif.
  • Eliahu A; Genentech, Inc, South San Francisco, Calif.
  • Durk MR; Genentech, Inc, South San Francisco, Calif.
  • Dengler HS; Genentech, Inc, South San Francisco, Calif.
  • Zak M; Genentech, Inc, South San Francisco, Calif.
  • Kenny JR; Genentech, Inc, South San Francisco, Calif.
  • Wilson ME; Genentech, Inc, South San Francisco, Calif.
  • Beasley R; Medical Research Institute of New Zealand, Wellington, New Zealand.
  • Chen H; Genentech, Inc, South San Francisco, Calif.
J Allergy Clin Immunol ; 148(3): 783-789, 2021 09.
Article em En | MEDLINE | ID: mdl-33744327

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos / Inibidores de Janus Quinases / Óxido Nítrico Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos / Inibidores de Janus Quinases / Óxido Nítrico Idioma: En Ano de publicação: 2021 Tipo de documento: Article