A wearable patch for continuous analysis of thermoregulatory sweat at rest.
Nat Commun
; 12(1): 1823, 2021 03 23.
Article
em En
| MEDLINE
| ID: mdl-33758197
ABSTRACT
The body naturally and continuously secretes sweat for thermoregulation during sedentary and routine activities at rates that can reflect underlying health conditions, including nerve damage, autonomic and metabolic disorders, and chronic stress. However, low secretion rates and evaporation pose challenges for collecting resting thermoregulatory sweat for non-invasive analysis of body physiology. Here we present wearable patches for continuous sweat monitoring at rest, using microfluidics to combat evaporation and enable selective monitoring of secretion rate. We integrate hydrophilic fillers for rapid sweat uptake into the sensing channel, reducing required sweat accumulation time towards real-time measurement. Along with sweat rate sensors, we integrate electrochemical sensors for pH, Cl-, and levodopa monitoring. We demonstrate patch functionality for dynamic sweat analysis related to routine activities, stress events, hypoglycemia-induced sweating, and Parkinson's disease. By enabling sweat analysis compatible with sedentary, routine, and daily activities, these patches enable continuous, autonomous monitoring of body physiology at rest.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Suor
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Sudorese
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Regulação da Temperatura Corporal
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Técnicas Biossensoriais
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Microfluídica
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Dispositivos Eletrônicos Vestíveis
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article