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Evaluation of Cortactin and HS1 Genes Expression: New Players in Adult B-Cell Acute Lymphoblastic leukemia.
Aref, Salah; Al Agdar, Mohamed; Ramez, Ahmed; Abou Zeid, Tarek; Sabry, Mohamed; Khaled, Nada.
Afiliação
  • Aref S; Hematology Unit, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt.
  • Al Agdar M; Hematology Unit, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt.
  • Ramez A; Medical Oncology Unit, Mansoura University Oncology Center (MUOC) Mansoura University, Egypt.
  • Abou Zeid T; Hematology Unit, Mansoura University Oncology Center (MUOC), Mansoura University, Egypt.
  • Sabry M; Hematology Unit, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt.
  • Khaled N; Hematology Unit, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt.
Asian Pac J Cancer Prev ; 22(3): 767-774, 2021 Mar 01.
Article em En | MEDLINE | ID: mdl-33773540
OBJECTIVES: This study aimed to assess the prognostic value of cortactin and HS1 genes expression in adult B-cell acute lymphoblastic leukemia. METHODS: The study included a cohort of 74 adult B-ALL patients and 76 controls. Cortactin and HS1 genes expression were quantified by real time PCR. RESULTS: The expression of cortactin and HS1 were significantly higher in B-ALL patients at diagnosis as compared to post induction levels (p.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas Adaptadoras de Transdução de Sinal / Cortactina Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas Adaptadoras de Transdução de Sinal / Cortactina Idioma: En Ano de publicação: 2021 Tipo de documento: Article