Further Evidence that Subsyndromal Manifestations of Depression in Childhood Predict the Subsequent Development of Major Depression: A Replication Study in a 10 Year Longitudinally Assessed Sample.
J Affect Disord
; 287: 101-106, 2021 05 15.
Article
em En
| MEDLINE
| ID: mdl-33774317
ABSTRACT
BACKGROUND:
We have previously shown that subsyndromal scores on the Child Behavior Checklist (CBCL)-Anxiety/Depression (Anx/Dep) scale at baseline predicted the subsequent development of Major Depressive Disorder (MDD) in youth with ADHD. The present study aimed to replicate these findings in a separate, long-term, longitudinal sample of children at high- and low- risk for depression.METHODS:
219 children of parents with and without depression and/or anxiety, ages 2-25, were stratified into 3 groups 1) children with familial risk for depression (by presence of parental MDD) plus subsyndromal scores on the CBCL-Anx/Dep scale, 2) children with familial risk for depression without subsyndromal scores, and 3) children with neither familial risk for depression nor subsyndromal scores. Subjects were reassessed at both 5 and 10 year follow-ups.RESULTS:
Children with both subsyndromal scores on the CBCL-Anx/Dep plus a familial risk for depression were at greater risk for developing MDD at the 10 year follow-up when compared with all other groups. Those with familial risk but no subsyndromal scores had an intermediate risk that was greater than the controls, who had the lowest risk.LIMITATIONS:
The recruitment of the study included families with parental panic disorder, so the sample likely included more families with anxiety disorders than the general population.CONCLUSIONS:
Our results showed that subsyndromal scores of the CBCL-Anx/Dep scale increased the risk for the subsequent development of MDD, particularly in children at high risk for depression. These results confirm the CBCL-Anx/Dep scale's utility in identifying children at high risk for developing MDD.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Filho de Pais com Deficiência
/
Transtorno de Pânico
/
Transtorno Depressivo Maior
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article