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Electrospinning for drug delivery applications: A review.
Luraghi, Andrea; Peri, Francesco; Moroni, Lorenzo.
Afiliação
  • Luraghi A; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, 20126 Milan, Italy.
  • Peri F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, 20126 Milan, Italy.
  • Moroni L; Complex Tissue Regeneration Department, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Universiteitssingel 40, 6229 ET Maastricht, the Netherlands. Electronic address: l.moroni@maastrichtuniversity.nl.
J Control Release ; 334: 463-484, 2021 06 10.
Article em En | MEDLINE | ID: mdl-33781809
ABSTRACT
Drug delivery devices are promising tools in the pharmaceutical field, as they are able to maximize the therapeutic effects of the delivered drug while minimizing the undesired side effects. In the past years, electrospun nanofibers attracted rising attention due to their unique features, like biocompatibility and broad flexibility. Incorporation of active principles in nanofibrous meshes proved to be an efficient method for in situ delivery of a wide range of drugs, expanding the possibility and applicability of those devices. In this review, the principle of electrospinning and different fields of applications are treated to give an overview of the recent literature, underlining the easy tuning and endless combination of this technique, that in the future could be the new frontier of personalized medicine.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Nanofibras Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Nanofibras Idioma: En Ano de publicação: 2021 Tipo de documento: Article