In Silico Analysis of P450s and Their Role in Secondary Metabolism in the Bacterial Class <i>Gammaproteobacteria</i>.

Msomi, Ntombizethu Nokuphiwa; Padayachee, Tiara; Nzuza, Nomfundo; Syed, Puleng Rosinah; Krys, Justyna Dorota; Chen, Wanping; Gront, Dominik; Nelson, David R; Syed, Khajamohiddin

In Silico Analysis of P450s and Their Role in Secondary Metabolism in the Bacterial Class Gammaproteobacteria.

Msomi, Ntombizethu Nokuphiwa; Padayachee, Tiara; Nzuza, Nomfundo; Syed, Puleng Rosinah; Krys, Justyna Dorota; Chen, Wanping; Gront, Dominik; Nelson, David R; Syed, Khajamohiddin.

Afiliação

Msomi NN; Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Padayachee T; Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Nzuza N; Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Syed PR; Department of Pharmaceutical Chemistry, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
Krys JD; Biological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Chen W; Department of Molecular Microbiology and Genetics, University of Göttingen, 37077 Göttingen, Germany.
Gront D; Biological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Nelson DR; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Syed K; Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.

Molecules ; 26(6)2021 Mar 11.

Article em En | MEDLINE | ID: mdl-33799696

Assuntos

Sistema Enzimático do Citocromo P-450/metabolismo; Gammaproteobacteria/genética; Gammaproteobacteria/metabolismo; Simulação por Computador; Cianobactérias; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/fisiologia; Evolução Molecular; Firmicutes; Genômica/métodos; Família Multigênica; Mycobacterium; Filogenia; Metabolismo Secundário/fisiologia; Streptomyces

Palavras-chave

Cyanobacteria; Firmicutes; Gammaproteobacteria; Mycobacterium; Streptomyces; biosynthetic gene clusters; cytochrome P450 monooxygenases; genome data mining; lifestyle; secondary metabolism

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gammaproteobacteria / Sistema Enzimático do Citocromo P-450 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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