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Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek, Kathrin; Byeon, Gun Woo; Kladwang, Wipapat; Wayment-Steele, Hannah K; Kerr, Craig H; Xu, Adele F; Kim, Do Soon; Topkar, Ved V; Choe, Christian; Rothschild, Daphna; Tiu, Gerald C; Wellington-Oguri, Roger; Fujii, Kotaro; Sharma, Eesha; Watkins, Andrew M; Nicol, John J; Romano, Jonathan; Tunguz, Bojan; Participants, Eterna; Barna, Maria; Das, Rhiju.
Afiliação
  • Leppek K; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Byeon GW; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Kladwang W; Department of Biochemistry, Stanford University, California 94305, USA.
  • Wayment-Steele HK; Department of Chemistry, Stanford University, Stanford, California 94305, USA.
  • Kerr CH; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Xu AF; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Kim DS; Department of Biochemistry, Stanford University, California 94305, USA.
  • Topkar VV; Program in Biophysics, Stanford University, Stanford, California 94305, USA.
  • Choe C; Department of Bioengineering, Stanford University, Stanford, California 94305, USA.
  • Rothschild D; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Tiu GC; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Wellington-Oguri R; Eterna Massive Open Laboratory.
  • Fujii K; Department of Genetics, Stanford University, Stanford, California 94305, USA.
  • Sharma E; Department of Biochemistry, Stanford University, California 94305, USA.
  • Watkins AM; Department of Biochemistry, Stanford University, California 94305, USA.
  • Nicol JJ; Eterna Massive Open Laboratory.
  • Romano J; Eterna Massive Open Laboratory.
  • Tunguz B; Department of Computer Science and Engineering, State University of New York at Buffalo, Buffalo, New York, 14260, USA.
  • Participants E; Department of Biochemistry, Stanford University, California 94305, USA.
  • Barna M; Eterna Massive Open Laboratory.
  • Das R; Department of Genetics, Stanford University, Stanford, California 94305, USA.
bioRxiv ; 2021 Mar 30.
Article em En | MEDLINE | ID: mdl-33821271
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article