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Uveitis-related Factors in Patients With Spondyloarthritis: TReasure Real-Life Results.
Yasar Bilge, Nazife Sule; Kalyoncu, Umut; Atagündüz, Pamir; Dalkiliç, Ediz; Pehlivan, Yavuz; Küçüksahin, Orhan; Bes, Cemal; Akar, Servet; Cinar, Muhammet; Emmungil, Hakan; Ersözlü, Duygu; Ates, Askin; Mercan, Ridvan; Kimyon, Gezmis; Koca, Süleyman Serdar; Gonullu, Emel; Yazisiz, Veli; Tekgöz, Emre; Alpay-Kanitez, Nilüfer; Erden, Abdulsamet; Kiraz, Sedat; Coskun, Belkis Nihan; Yagiz, Burcu; Ilgen, Ufuk; Karadag, Ömer; Kilic, Levent; Ertenli, Ihsan; Kasifoglu, Timuçin.
Afiliação
  • Yasar Bilge NS; From the Division of Rheumatology, Department of Internal Medicine, Eskisehir Osmangazi University, Eskisehir.
  • Kalyoncu U; Division of Rheumatology, Department of Internal Medicine, Hacettepe University, Ankara. Electronic address: umut.kalyoncu@yahoo.com.
  • Atagündüz P; Division of Rheumatology, Department of Internal Medicine, Marmara University, Istanbul.
  • Dalkiliç E; Division of Rheumatology, Department of Internal Medicine, Uludag University, Bursa.
  • Pehlivan Y; Division of Rheumatology, Department of Internal Medicine, Uludag University, Bursa.
  • Küçüksahin O; Division of Rheumatology, Department of Internal Medicine, Ankara Yildirim Beyazit University, Ankara City Hospital, Ankara.
  • Bes C; Division of Rheumatology, Department of Internal Medicine, University of Health Sciences, Istanbul Basaksehir Cam and Sakura City Hospital, Istanbul.
  • Akar S; Division of Rheumatology, Department of Internal Medicine, Izmir Katip Celebi Univeristy, Izmir.
  • Cinar M; Division of Rheumatology, Department of Internal Medicine, University of Health Sciences Turkey, Ankara.
  • Emmungil H; Division of Rheumatology, Department of Internal Medicine, Trakya University, Edirne.
  • Ersözlü D; Division of Rheumatology, Department of Internal Medicine, Adana City Training and Research Hospital, Adana.
  • Ates A; Division of Rheumatology, Department of Internal Medicine, Medical Faculty, Ankara University, Ankara.
  • Mercan R; Division of Rheumatology, Department of Internal Medicine, Namik Kemal University, Tekirdag.
  • Kimyon G; Division of Rheumatology, Department of Internal Medicine, Mustafa Kemal University, Hatay.
  • Koca SS; Division of Rheumatology, Department of Internal Medicine, Firat University, Elazig.
  • Gonullu E; Division of Rheumatology, Department of Internal Medicine, Sakarya University, Sakarya.
  • Yazisiz V; Division of Rheumatology, Department of Internal Medicine, Akdeniz University, Antalya.
  • Tekgöz E; Division of Rheumatology, Department of Internal Medicine, University of Health Sciences Turkey, Ankara.
  • Alpay-Kanitez N; Division of Rheumatology, Department of Internal Medicine, Koç University, Isparta.
  • Erden A; Division of Rheumatology, Department of Internal Medicine, Ankara City Hospital, Ankara.
  • Kiraz S; Division of Rheumatology, Department of Internal Medicine, Hacettepe University, Ankara.
  • Coskun BN; Division of Rheumatology, Department of Internal Medicine, Uludag University, Bursa.
  • Yagiz B; Division of Rheumatology, Department of Internal Medicine, Uludag University, Bursa.
  • Ilgen U; Division of Rheumatology, Department of Internal Medicine, Trakya University, Edirne.
  • Karadag Ö; Division of Rheumatology, Department of Internal Medicine, Hacettepe University, Ankara.
  • Kilic L; Division of Rheumatology, Department of Internal Medicine, Hacettepe University, Ankara.
  • Ertenli I; Division of Rheumatology, Department of Internal Medicine, Hacettepe University, Ankara.
  • Kasifoglu T; From the Division of Rheumatology, Department of Internal Medicine, Eskisehir Osmangazi University, Eskisehir.
Am J Ophthalmol ; 228: 58-64, 2021 08.
Article em En | MEDLINE | ID: mdl-33826929
ABSTRACT

PURPOSE:

Spondyloarthritis (SpA) is a group of diseases with overlapping skeletal and extra-articular features. Acute anterior uveitis (AAU) is the most common extra-articular manifestation of SpA. The relation between AAU and SpA is well defined in the current literature. Our study aims to analyze the frequency and factors associated with AAU in different forms of SpA in a large nationwide cohort of Turkish SpA patients.

DESIGN:

Retrospective cohort study.

METHODS:

The data were obtained from the TReasure database, which compiles data from records of the web-based Rheumatoid Arthritis (RA) and SpA patients treated with biological disease-modifying anti-rheumatismal drugs from different regions of Turkey. The clinical characteristics of SpA and uveitis are recorded.

RESULTS:

Data of the 4,297 SpA patients were included in the study. Overall, 475 of 4,297 patients (11.0%) had experienced 1 or more episodes of uveitis. SpA patients with older age (P < .001), a smoking history (P = .004), delayed diagnosis (P = .001), longer disease duration (P < .001), arthritis (P < .001), positive HLA-B27 (P < .001), a family history of SpA (P < .001), and radiographic damage (presence of sacroiliitis, syndesmophytes, bamboo spine, hip involvement) (P < .001 for all) more commonly had uveitis. On the other hand, uveitis was less prevalent in patients with psoriasis and psoriatic arthritis (P < .001 for both).

CONCLUSION:

Uveitis may be the key feature leading to SpA diagnosis. Patients with radiographic damage and long disease duration have an increased risk for uveitis in both male and female SpA patients. Patients with uveitis should be referred to a rheumatologist for a thorough evaluation of SpA.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espondilite Anquilosante / Uveíte Anterior Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espondilite Anquilosante / Uveíte Anterior Idioma: En Ano de publicação: 2021 Tipo de documento: Article