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C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.
Fumagalli, Laura; Young, Florence L; Boeynaems, Steven; De Decker, Mathias; Mehta, Arpan R; Swijsen, Ann; Fazal, Raheem; Guo, Wenting; Moisse, Matthieu; Beckers, Jimmy; Dedeene, Lieselot; Selvaraj, Bhuvaneish T; Vandoorne, Tijs; Madan, Vanesa; van Blitterswijk, Marka; Raitcheva, Denitza; McCampbell, Alexander; Poesen, Koen; Gitler, Aaron D; Koch, Philipp; Vanden Berghe, Pieter; Thal, Dietmar Rudolf; Verfaillie, Catherine; Chandran, Siddharthan; Van Den Bosch, Ludo; Bullock, Simon L; Van Damme, Philip.
Afiliação
  • Fumagalli L; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Young FL; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Boeynaems S; Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, UK.
  • De Decker M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Mehta AR; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Swijsen A; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Fazal R; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.
  • Guo W; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Moisse M; The Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, UK.
  • Beckers J; The Euan MacDonald Centre, University of Edinburgh, Edinburgh, UK.
  • Dedeene L; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Selvaraj BT; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Vandoorne T; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Madan V; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • van Blitterswijk M; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Raitcheva D; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • McCampbell A; KU Leuven-University of Leuven, Department of Development and Regeneration, Stem Cell Institute, Leuven, Belgium.
  • Poesen K; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Gitler AD; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Koch P; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Vanden Berghe P; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Thal DR; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Verfaillie C; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
  • Chandran S; KU Leuven-University of Leuven, Department of Neurosciences, Laboratory for Molecular Neurobiomarker Research and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Van Den Bosch L; KU Leuven-University of Leuven, Department of Imaging and Pathology, Laboratory for Neuropathology and Leuven Brain Institute (LBI), Leuven, Belgium.
  • Bullock SL; Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.
  • Van Damme P; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.
Sci Adv ; 7(15)2021 04.
Article em En | MEDLINE | ID: mdl-33837088
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2021 Tipo de documento: Article