Cancer biology: Messages in extracellular vesicles depend on centrosome number.

Jewett, Cayla E; Pearson, Chad G

Jewett, Cayla E; Pearson, Chad G.

Afiliação

Jewett CE; Department of Cell and Developmental Biology, University of Colorado - Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: Cayla.Jewett@cuanschutz.edu.
Pearson CG; Department of Cell and Developmental Biology, University of Colorado - Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: Chad.Pearson@cuanschutz.edu.

Curr Biol ; 31(7): R337-R340, 2021 04 12.

Article em En | MEDLINE | ID: mdl-33848487

ABSTRACT

ABSTRACT

Extra centrosomes are linked to cancer-associated errors in cell division, metastasis and signaling. A new study reveals that centrosome amplification disrupts lysosome function, leading to the release of small extracellular vesicles and to invasive activity in pancreatic cells.

Assuntos

Vesículas Extracelulares; Neoplasias; Biologia; Divisão Celular; Centrossomo; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vesículas Extracelulares / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vesículas Extracelulares / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article