More than neutrophils: Lin(+)Ly6G(+)IL-5R&#945;(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes.

Jeong, Brian M; Walker, Matthew T; Rodriguez, Raul; Coden, Mackenzie E; Nagasaka, Reina; Doan, Ton C; Politanska, Yuliya; Abdala-Valencia, Hiam; Berdnikovs, Sergejs

More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes.

Jeong, Brian M; Walker, Matthew T; Rodriguez, Raul; Coden, Mackenzie E; Nagasaka, Reina; Doan, Ton C; Politanska, Yuliya; Abdala-Valencia, Hiam; Berdnikovs, Sergejs.

Afiliação

Jeong BM; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Walker MT; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Rodriguez R; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Coden ME; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Nagasaka R; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Doan TC; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Politanska Y; Division of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Abdala-Valencia H; Division of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Berdnikovs S; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

J Leukoc Biol ; 111(1): 113-122, 2022 01.

Article em En | MEDLINE | ID: mdl-33857341

Assuntos

Antígenos Ly/análise; Eosinófilos/citologia; Subunidade alfa de Receptor de Interleucina-5/análise; Monócitos/citologia; Células Progenitoras Mieloides/citologia; Neutrófilos/citologia; Animais; Células da Medula Óssea/citologia; Diferenciação Celular; Células Cultivadas; Feminino; Leucopoese; Masculino; Camundongos Endogâmicos BALB C

Palavras-chave

bone marrow; eosinophils; flow cytometry; hematopoiesis; heterogeneity; homeostasis; macrophages; monocytes; neutrophils; plasticity; transcription factors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Antígenos Ly / Células Progenitoras Mieloides / Eosinófilos / Subunidade alfa de Receptor de Interleucina-5 / Neutrófilos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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