Human Schlafen 5 Inhibits Proliferation and Promotes Apoptosis in Lung Adenocarcinoma via the PTEN/PI3K/AKT/mTOR Pathway.

Gu, Xuefeng; Zhou, Li; Chen, Lei; Pan, Huiqing; Zhao, Rui; Guang, Weiwei; Wan, Guoqing; Zhang, Peng; Liu, Dingsheng; Deng, Li-Li; Zhao, Weiming; Lu, Changlian

Gu, Xuefeng; Zhou, Li; Chen, Lei; Pan, Huiqing; Zhao, Rui; Guang, Weiwei; Wan, Guoqing; Zhang, Peng; Liu, Dingsheng; Deng, Li-Li; Zhao, Weiming; Lu, Changlian.

Afiliação

Gu X; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Zhou L; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Chen L; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Pan H; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Zhao R; Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Guang W; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Wan G; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Zhang P; Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Liu D; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Deng LL; Shanghai University of Medicine & Health Science Affiliated Zhoupu Hospital, Shanghai, China.
Zhao W; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Lu C; Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.

Biomed Res Int ; 2021: 6628682, 2021.

Article em En | MEDLINE | ID: mdl-33860045

Assuntos

Adenocarcinoma de Pulmão/patologia; Apoptose; Proteínas de Ciclo Celular/metabolismo; Neoplasias Pulmonares/patologia; PTEN Fosfo-Hidrolase/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Células A549; Adenocarcinoma de Pulmão/genética; Adenocarcinoma de Pulmão/metabolismo; Animais; Proliferação de Células; Regulação Neoplásica da Expressão Gênica; Técnicas de Silenciamento de Genes; Glicogênio Sintase Quinase 3 beta/metabolismo; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Camundongos Nus; Fosforilação; Transdução de Sinais; Transcrição Gênica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Proteínas de Ciclo Celular / Fosfatidilinositol 3-Quinases / PTEN Fosfo-Hidrolase / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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