LINC00665 activates Wnt/ß-catenin signaling pathway to facilitate tumor progression of colorectal cancer via upregulating CTNNB1.

Han, Ting; Gao, Mingbo; Wang, Xin; Li, Wei; Zhuo, Jialu; Qu, Zhihua; Chen, Yiqiu

Han, Ting; Gao, Mingbo; Wang, Xin; Li, Wei; Zhuo, Jialu; Qu, Zhihua; Chen, Yiqiu.

Afiliação

Han T; Department of Clinical Nutrition, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address: sykyc@188.com.
Gao M; Department of Clinical Nutrition, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Wang X; Department of Nutrition, Taicang Affiliated Hospital of Soochow University, the First People's Hospital of Taicang, Taicang, 215400, Jiangsu, China.
Li W; Department of Clinical Nutrition, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Zhuo J; Department of Clinical Nutrition, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Qu Z; Department of Clinical Nutrition, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Chen Y; Department of Clinical Nutrition, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

Exp Mol Pathol ; 120: 104639, 2021 06.

Article em En | MEDLINE | ID: mdl-33865827

Assuntos

Biomarcadores Tumorais/metabolismo; Neoplasias Colorretais/patologia; Regulação Neoplásica da Expressão Gênica; MicroRNAs/genética; RNA Longo não Codificante/genética; Proteína Wnt1/metabolismo; beta Catenina/metabolismo; Animais; Apoptose; Biomarcadores Tumorais/genética; Movimento Celular; Proliferação de Células; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Feminino; Humanos; Camundongos; Camundongos Nus; Células Tumorais Cultivadas; Proteína Wnt1/genética; Ensaios Antitumorais Modelo de Xenoenxerto; beta Catenina/genética

Palavras-chave

CTNNB1; LINC00665; U2AF2; Wnt/ß-catenin signaling pathway; miR-214-3p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / MicroRNAs / Proteína Wnt1 / Beta Catenina / RNA Longo não Codificante Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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