PTEN mutations predict benefit from tumor treating fields (TTFields) therapy in patients with recurrent glioblastoma.

Dono, Antonio; Mitra, Sonali; Shah, Mauli; Takayasu, Takeshi; Zhu, Jay-Jiguang; Tandon, Nitin; Patel, Chirag B; Esquenazi, Yoshua; Ballester, Leomar Y

Dono, Antonio; Mitra, Sonali; Shah, Mauli; Takayasu, Takeshi; Zhu, Jay-Jiguang; Tandon, Nitin; Patel, Chirag B; Esquenazi, Yoshua; Ballester, Leomar Y.

Afiliação

Dono A; Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.
Mitra S; Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.
Shah M; Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.
Takayasu T; Rice University, Houston, TX, 77030, USA.
Zhu JJ; Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.
Tandon N; Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.
Patel CB; Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.
Esquenazi Y; Memorial Hermann Hospital-TMC, Houston, TX, 77030, USA.
Ballester LY; Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, 77030, USA.

J Neurooncol ; 153(1): 153-160, 2021 May.

Article em En | MEDLINE | ID: mdl-33881725

Assuntos

Neoplasias Encefálicas; Glioblastoma; PTEN Fosfo-Hidrolase/genética; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/terapia; Doença Crônica; Glioblastoma/genética; Glioblastoma/terapia; Humanos; Mutação; Recidiva; Estudos Retrospectivos

Palavras-chave

IDH-wildtype; PTEN; Predictive biomarker; Recurrent glioblastoma; Tumor treating fields (TTFields)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / PTEN Fosfo-Hidrolase Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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