Burst Exercise Testing Can Unmask Arrhythmias in Patients With Incompletely Penetrant Catecholaminergic Polymorphic Ventricular Tachycardia.
JACC Clin Electrophysiol
; 7(4): 437-441, 2021 04.
Article
em En
| MEDLINE
| ID: mdl-33888264
ABSTRACT
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by cardiac arrest during sudden exertion. However, standard exercise stress testing (EST) lacks sensitivity, leading to misdiagnosis and undertreatment. After a nondiagnostic standard gradual EST, we report 6 patients who underwent a novel burst exercise test characterized by sudden high workload at the outset of testing. In 5 of 6 patients, the burst EST induced new and more complex arrhythmias versus standard EST, which compelled medication initiation in 3 patients. We postulate that this simple EST modification better mimics a typical CPVT triggering event and could improve diagnostic sensitivity and therapeutic decision making.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Taquicardia Ventricular
/
Teste de Esforço
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article