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Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition.
Ghanim, Amany M; Rezq, Samar; Ibrahim, Tarek S; Romero, Damian G; Kothayer, Hend.
Afiliação
  • Ghanim AM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, 44519, Egypt.
  • Rezq S; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Egypt; Departments of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS, USA; Mississippi Center for Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson
  • Ibrahim TS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, 44519, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
  • Romero DG; Departments of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS, USA; Mississippi Center for Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS, USA; Women's Health Research Center, University of Mississippi Medical Center, Jackso
  • Kothayer H; Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Egypt. Electronic address: hendo1311@hotmail.com.
Eur J Med Chem ; 219: 113457, 2021 Jul 05.
Article em En | MEDLINE | ID: mdl-33892270
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Triazinas / Araquidonato 15-Lipoxigenase / Ciclo-Oxigenase 2 / Anti-Inflamatórios Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Triazinas / Araquidonato 15-Lipoxigenase / Ciclo-Oxigenase 2 / Anti-Inflamatórios Idioma: En Ano de publicação: 2021 Tipo de documento: Article