Prolonged Response to HER2-Directed Therapy in Three Patients with HER2-Amplified Metastatic Carcinoma of the Biliary System: Case Study and Review of the Literature.

May, Michael; Raufi, Alexander G; Sadeghi, Sina; Chen, Karen; Iuga, Alina; Sun, Yu; Ahmed, Firas; Bates, Susan; Manji, Gulam A

May, Michael; Raufi, Alexander G; Sadeghi, Sina; Chen, Karen; Iuga, Alina; Sun, Yu; Ahmed, Firas; Bates, Susan; Manji, Gulam A.

Afiliação

May M; Division of Hematology and Oncology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, New York, USA.
Raufi AG; Division of Hematology and Oncology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, New York, USA.
Sadeghi S; Division of Hematology-Oncology, Lifespan Cancer Institute, Warren-Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Chen K; Division of Hematology and Oncology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, New York, USA.
Iuga A; Division of Hematology and Oncology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, New York, USA.
Sun Y; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Ahmed F; Department of Pathology, Columbia University Medical Center, New York, New York, USA.
Bates S; Department of Radiology, Columbia University Medical Center, New York, New York, USA.
Manji GA; Division of Hematology and Oncology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, New York, USA.

Oncologist ; 26(8): 640-646, 2021 08.

Article em En | MEDLINE | ID: mdl-33896096

Assuntos

Adenocarcinoma; Neoplasias do Sistema Biliar; Sistema Biliar; Neoplasias Gástricas; Adenocarcinoma/genética; Sistema Biliar/metabolismo; Neoplasias do Sistema Biliar/tratamento farmacológico; Neoplasias do Sistema Biliar/genética; Amplificação de Genes; Humanos; Receptor ErbB-2/genética; Receptor ErbB-2/metabolismo; Neoplasias Gástricas/tratamento farmacológico; Neoplasias Gástricas/genética

Palavras-chave

Ampullary carcinoma; Biliary tract cancer; Gallbladder carcinoma; HER2 amplification; Precision medicine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Sistema Biliar / Neoplasias do Sistema Biliar / Adenocarcinoma Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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