Far-infrared irradiation inhibits breast cancer cell proliferation independently of DNA damage through increased nuclear Ca<sup>2+</sup>/calmodulin binding modulated-activation of checkpoint kinase 2.

Cho, Du-Hyong; Lee, Hyeon-Ju; Lee, Jee Young; Park, Jung-Hyun; Jo, Inho

Far-infrared irradiation inhibits breast cancer cell proliferation independently of DNA damage through increased nuclear Ca²⁺/calmodulin binding modulated-activation of checkpoint kinase 2.

Cho, Du-Hyong; Lee, Hyeon-Ju; Lee, Jee Young; Park, Jung-Hyun; Jo, Inho.

Afiliação

Cho DH; Department of Pharmacology, Yeungnam University College of Medicine, 170 Hyunchung-ro, Nam-gu, Daegu 42415, Republic of Korea.
Lee HJ; Department of Molecular Medicine, College of Medicine, Graduate Program in System Health Science and Engineering, Ewha Womans University, 25 Magokdong-ro-2-gil, Gangseo-gu, Seoul 07804, South Korea.
Lee JY; Department of Molecular Medicine, College of Medicine, Graduate Program in System Health Science and Engineering, Ewha Womans University, 25 Magokdong-ro-2-gil, Gangseo-gu, Seoul 07804, South Korea.
Park JH; Department of Molecular Medicine, College of Medicine, Graduate Program in System Health Science and Engineering, Ewha Womans University, 25 Magokdong-ro-2-gil, Gangseo-gu, Seoul 07804, South Korea. Electronic address: hapblover@ewha.ac.kr.
Jo I; Department of Molecular Medicine, College of Medicine, Graduate Program in System Health Science and Engineering, Ewha Womans University, 25 Magokdong-ro-2-gil, Gangseo-gu, Seoul 07804, South Korea. Electronic address: inhojo@ewha.ac.kr.

J Photochem Photobiol B ; 219: 112188, 2021 Jun.

Article em En | MEDLINE | ID: mdl-33901880

Assuntos

Cálcio/metabolismo; Calmodulina/metabolismo; Proliferação de Células/efeitos da radiação; Quinase do Ponto de Checagem 2/metabolismo; Dano ao DNA/efeitos da radiação; Raios Infravermelhos; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; Núcleo Celular/metabolismo; Sobrevivência Celular/efeitos da radiação; Quinase do Ponto de Checagem 2/antagonistas & inibidores; Quinase do Ponto de Checagem 2/genética; Feminino; Humanos; Fosforilação/efeitos da radiação; Ligação Proteica; Interferência de RNA; RNA Interferente Pequeno/metabolismo; Regulação para Cima/efeitos da radiação

Palavras-chave

Calcium; Calmodulin; Cancer cell proliferation; Checkpoint kinase 2; Far-infrared irradiation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Calmodulina / Cálcio / Proliferação de Células / Quinase do Ponto de Checagem 2 / Raios Infravermelhos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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