Making sense of associations between type 2 diabetes, metformin, and breast cancer risk.

Park, Yong-Moon Mark; Sandler, Dale P

Park, Yong-Moon Mark; Sandler, Dale P.

Afiliação

Park YM; Department of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.

Br J Cancer ; 125(7): 909-910, 2021 09.

Article em En | MEDLINE | ID: mdl-33911196

ABSTRACT

ABSTRACT

The relationship between type 2 diabetes (T2D), metformin, and breast cancer is complex. T2D may increase risk, but metformin used as first-line treatment of T2D may decrease breast cancer risk. This comment explores efforts to disentangle effects of T2D and metformin use on breast cancer risk in a prospective study.

Assuntos

Neoplasias da Mama/epidemiologia; Diabetes Mellitus Tipo 2/tratamento farmacológico; Metformina/uso terapêutico; Neoplasias da Mama/metabolismo; Neoplasias da Mama/prevenção & controle; Diabetes Mellitus Tipo 2/metabolismo; Feminino; Humanos; Estudos Prospectivos; Receptores de Estrogênio/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Diabetes Mellitus Tipo 2 / Metformina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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