Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development.

Fuhrmann, Lars; Lindner, Saskia; Hauser, Alexander-Thomas; Höse, Clemens; Kretz, Oliver; Cohen, Clemens D; Lindenmeyer, Maja T; Sippl, Wolfgang; Jung, Manfred; Huber, Tobias B; Wanner, Nicola

Fuhrmann, Lars; Lindner, Saskia; Hauser, Alexander-Thomas; Höse, Clemens; Kretz, Oliver; Cohen, Clemens D; Lindenmeyer, Maja T; Sippl, Wolfgang; Jung, Manfred; Huber, Tobias B; Wanner, Nicola.

Afiliação

Fuhrmann L; III Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Lindner S; Department of Medicine IV, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Hauser AT; Institute of Pharmaceutical Sciences, University of Freiburg, 79104 Freiburg, Germany.
Höse C; Department of Medicine IV, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Kretz O; III Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Cohen CD; Nephrological Center, Medical Clinic and Policlinic IV, University of Munich, 80336 Munich, Germany.
Lindenmeyer MT; III Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Sippl W; Institute of Pharmacy, Martin-Luther-University of Halle-Wittenberg, 06120 Halle (Saale), Germany.
Jung M; Institute of Pharmaceutical Sciences, University of Freiburg, 79104 Freiburg, Germany.
Huber TB; CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
Wanner N; III Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Int J Mol Sci ; 22(8)2021 Apr 16.

Article em En | MEDLINE | ID: mdl-33923831

Assuntos

Nefropatias Diabéticas/genética; Meio Ambiente; Epigênese Genética; Glucose/toxicidade; Rim/metabolismo; Efeitos Tardios da Exposição Pré-Natal/genética; Animais; Metilação de DNA; Feminino; Humanos; Deficiências de Ferro; Rim/efeitos dos fármacos; Camundongos; Técnicas de Cultura de Órgãos/métodos; Gravidez; Transcriptoma

Palavras-chave

DNA methylation; diabetic nephropathy; epigenetic regulation; iron deficiency; nephron number; renal development

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Epigênese Genética / Nefropatias Diabéticas / Meio Ambiente / Glucose / Rim Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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