Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial.

Pratt, Arthur G; Siebert, Stefan; Cole, Michael; Stocken, Deborah D; Yap, Christina; Kelly, Stephen; Shaikh, Muddassir; Cranston, Amy; Morton, Miranda; Walker, Jenn; Frame, Sheelagh; Ng, Wan-Fai; Buckley, Christopher D; McInnes, Iain B; Filer, Andrew; Isaacs, John D.

Afiliação

Pratt AG; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Siebert S; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Cole M; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
Stocken DD; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Yap C; Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.
Kelly S; Clinical Trial and Statistics Unit, The Institute of Cancer Research, London, UK.
Shaikh M; Department of Rheumatology, Barts Health NHS Trust, London, UK.
Cranston A; Department of Rheumatology, James Cook University Hospital, Middlesbrough, UK.
Morton M; Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
Walker J; Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
Frame S; Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK.
Ng WF; Cyclacel, Dundee, UK.
Buckley CD; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
McInnes IB; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Filer A; National Institute for Health Research Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust and Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
Isaacs JD; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.

Lancet Rheumatol ; 3(5): e337-e346, 2021 May.

Article em En | MEDLINE | ID: mdl-33928262

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article