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Risk Factors for Perforation During Endoscopic Papillary Large Balloon Dilation and Bile Duct Stone Removal.
Yamauchi, Hiroshi; Iwai, Tomohisa; Okuwaki, Kosuke; Miyata, Eiji; Kawaguchi, Yusuke; Matsumoto, Takaaki; Uehara, Kazuho; Tamaki, Akihiro; Araki, Masao; Ohno, Takashi; Imaizumi, Hiroshi; Kida, Mitsuhiro; Koizumi, Wasaburo.
Afiliação
  • Yamauchi H; Department of Gastroenterology, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan. yhiroshi@kitasato-u.ac.jp.
  • Iwai T; Department of Gastroenterology, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan.
  • Okuwaki K; Department of Gastroenterology, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan.
  • Miyata E; Department of Gastroenterology, Sagamihara Kyodo Hospital, Sagamihara, Japan.
  • Kawaguchi Y; Department of Gastroenterology, Kitasato University Medical Center, Kitamoto, Japan.
  • Matsumoto T; Department of Gastroenterology, Isehara Kyodo Hospital, Isehara, Japan.
  • Uehara K; Department of Gastroenterology, Kitasato University Medical Center, Kitamoto, Japan.
  • Tamaki A; Department of Gastroenterology, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan.
  • Araki M; Department of Gastroenterology, Sagamihara Kyodo Hospital, Sagamihara, Japan.
  • Ohno T; Department of Gastroenterology, Isehara Kyodo Hospital, Isehara, Japan.
  • Imaizumi H; Department of Gastroenterology, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan.
  • Kida M; Department of Gastroenterology, Kitasato University Medical Center, Kitamoto, Japan.
  • Koizumi W; Department of Gastroenterology, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan.
Dig Dis Sci ; 67(5): 1890-1900, 2022 05.
Article em En | MEDLINE | ID: mdl-33932200
ABSTRACT

BACKGROUND:

Stone removal using endoscopic papillary large balloon dilation (EPLBD) is extremely effective. However, limited research exists regarding the risk factors for perforation of the duodenal papilla and bile duct, which may be fatal.

AIMS:

We aimed to investigate the risk factors for perforation during EPLBD + stone removal.

METHODS:

We included patients who underwent EPLBD + stone removal at four medical facilities between January 2008 and December 2018. We retrospectively analyzed the risk factors for perforation and their relationship between overdilation and adverse events. Overdilation was defined as a ratio of the balloon diameter to the diameter of the bile duct that exceeded 100%. The diameter of the distal bile duct was measured using the diameter of the intrapancreatic bile duct at a point 10 mm toward the liver from the narrow distal segment on a cholangiogram.

RESULTS:

We included 310 patients (177 males; median age 79 years [range 46-102 years]). Perforation occurred in five patients (1.6%). Multivariate analysis indicated that no surrounding-pancreas (half or less of the circumference of the intrapancreatic bile duct was surrounded by the pancreatic parenchyma) was a significant risk factor (perforation rate 8.3%, p = 0.011, odds ratio 12.7 [95% confidence interval 1.8-90.5]). No significant difference was found between the overdilation and non-overdilation groups regarding the occurrence of pancreatitis, bleeding, and cholangitis. Perforation rate in patients with no surrounding pancreas + overdilation was 16.7% (2/12). Patients with perforation underwent conservative therapy, which improved their conditions.

CONCLUSIONS:

EPLBD + stone removal should be avoided in patients with no surrounding pancreas. Overdilation is not a risk factor for adverse procedural events; however, it should be limited in patients with surrounding pancreas.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálculos Biliares / Esfinterotomia Endoscópica Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cálculos Biliares / Esfinterotomia Endoscópica Idioma: En Ano de publicação: 2022 Tipo de documento: Article