Safety and efficacy of BAY 94-9027, an extended-half-life factor VIII, during minor surgical procedures in patients with severe haemophilia A.

Santagostino, Elena; Lalezari, Shadan; Reding, Mark T; Ducore, Jonathan; Ng, Heng Joo; Poulsen, Lone H; Michaels, Lisa A; Linardi, Camila

Santagostino, Elena; Lalezari, Shadan; Reding, Mark T; Ducore, Jonathan; Ng, Heng Joo; Poulsen, Lone H; Michaels, Lisa A; Linardi, Camila.

Afiliação

Santagostino E; Foundation IRCCS Ca' Granda, Maggiore Hospital Policlinico A. Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
Lalezari S; Israel National Hemophilia Center, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Reding MT; Sackler School of Medicine, Tel-Aviv University, Tel Hashomer, Israel.
Ducore J; Center for Bleeding and Clotting Disorders, University of Minnesota Medical Center, Minneapolis, MN, USA.
Ng HJ; Hemophilia Treatment Center, UC Davis Medical Center, Sacramento, CA, USA.
Poulsen LH; Department of Haematology, Singapore General Hospital, Singapore.
Michaels LA; The Haemophilia Centre, Aarhus University Hospital, Aarhus, Denmark.
Linardi C; Bayer, Whippany, NJ, USA.

Haemophilia ; 27(4): e559-e562, 2021 Jul.

Article em En | MEDLINE | ID: mdl-33939226

Assuntos

Fator VIII; Hemofilia A; Fator VIII/uso terapêutico; Meia-Vida; Hemofilia A/tratamento farmacológico; Humanos; Procedimentos Cirúrgicos Menores; Polietilenoglicóis; Resultado do Tratamento

Palavras-chave

PEGylation; clinical outcome; clinical trials; extended half-life; factor VIII; haemophilia A; minor surgery

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator VIII / Hemofilia A Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator VIII / Hemofilia A Idioma: En Ano de publicação: 2021 Tipo de documento: Article