siRNA Therapeutics for the Therapy of COVID-19 and Other Coronaviruses.

Sajid, Muhammad Imran; Moazzam, Muhammad; Cho, Yeseom; Kato, Shun; Xu, Ava; Way, J J; Lohan, Sandeep; Tiwari, Rakesh K

Sajid, Muhammad Imran; Moazzam, Muhammad; Cho, Yeseom; Kato, Shun; Xu, Ava; Way, J J; Lohan, Sandeep; Tiwari, Rakesh K.

Afiliação

Sajid MI; Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, California 92618, United States.
Moazzam M; Faculty of Pharmacy, University of Central Punjab, Lahore 54700, Pakistan.
Cho Y; Faculty of Pharmacy, University of Central Punjab, Lahore 54700, Pakistan.
Kato S; Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, California 92618, United States.
Xu A; Department of Biochemistry and Molecular Biology, Schmid College of Science and Technology, Chapman University, Orange, California 92866, United States.
Way JJ; Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, California 92618, United States.
Lohan S; Department of Biochemistry and Molecular Biology, Schmid College of Science and Technology, Chapman University, Orange, California 92866, United States.
Tiwari RK; Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, California 92618, United States.

Mol Pharm ; 18(6): 2105-2121, 2021 06 07.

Article em En | MEDLINE | ID: mdl-33945284

Assuntos

Antivirais/uso terapêutico; Tratamento Farmacológico da COVID-19; Pandemias/prevenção & controle; RNA Interferente Pequeno/uso terapêutico; SARS-CoV-2/genética; Antivirais/história; COVID-19/epidemiologia; COVID-19/história; COVID-19/virologia; Ensaios Clínicos como Assunto; Aprovação de Drogas; Avaliação Pré-Clínica de Medicamentos; História do Século XX; História do Século XXI; Humanos; Mutação; Patentes como Assunto; RNA Interferente Pequeno/história; SARS-CoV-2/patogenicidade

Palavras-chave

COVID-19; SARS-CoV-2; coronaviruses; dsRNA; nucleic acid therapy; patents; siRNA delivery; siRNA therapy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA Interferente Pequeno / Pandemias / SARS-CoV-2 / Tratamento Farmacológico da COVID-19 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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